Biotechnology-Driven Integrated Medication Management for Chronic Disease Care: Advancing Community Health Through Digital Health Solutions

Wei Wang
Zhoujiaqiao Community Health Care Center, Shanghai, 200051, China

DOI:https://doi.org/10.5912/jcb1802

Abstract:

This study explores the application of biotechnology-driven approaches in integrated medication management for patients with common chronic diseases, leveraging digital health technologies to enhance therapeutic efficacy and patient adherence. Recognizing that chronic disease treatment often requires long-term pharmacological interventions, this research focuses on optimizing drug combinations and minimizing side effects through bioinformatics and pharmacogenomic analysis. By determining the average shortest distance of drug targets within human protein interaction networks and analyzing the similarity characteristics of cellular signaling pathways, the study designs optimal drug regimens tailored to individual patient profiles. Additionally, common and non-common differentially expressed genes from pharmacogenomic data were integrated for feature optimization in medication management strategies. An integrated medication management program, grounded in digital health principles, was developed to improve rational medication self-efficacy and patient motivation. The program’s effectiveness was evaluated through a controlled intervention study. Results demonstrated that, after one month of intervention, the self-efficacy of medication use in the intervention group reached 29.15, significantly higher than the control group’s 23.89. Furthermore, after three months, the motivation level for medication adherence in the intervention group was 25.58, compared to 22.03 in the control group. These findings underscore the potential of combining biotechnology and digital health solutions to personalize medication management for chronic disease patients. The integration of bioinformatics, pharmacogenomics, and digital health technologies not only optimizes therapeutic outcomes but also enhances patient engagement and adherence. This research highlights promising commercial opportunities for biotechnology applications in community health management, offering scalable solutions for improving chronic disease care and supporting the growing demand for personalized healthcare systems.