Research Progress of Arterial Resection Reconstruction and Arterial Sheath Removal in the Treatment of Locally Advanced Pancreatic Cancer Involving Arteries

Qingqing Lan
Guizhou Medical University, Department of Hepatobiliary Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang 550000, China
Haifeng Yang
Guizhou Medical University, Department of Hepatobiliary Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang 550000, China

Abstract:

At present, radical resection is still the preferred treatment for pancreatic cancer, and the surgical resection rate of pancreatic cancer diagnosed in early stage can reach 70%~80%, and in advanced cases, the resectable rate is only 15%~20%, especially for locally advanced pancreatic cancer that invades the artery, the surgical resection rate is even lower. With the continuous advancement of surgical techniques, arterial resection and reconstruction techniques and arterial sheath removal techniques provide new hope for the treatment of patients with locally advanced pancreatic cancer with arterial invasion. The arterial resection reconstruction technique is suitable for patients with locally advanced pancreatic cancer whose tumor has invaded the artery but has not developed distant metastases. By removing the invaded artery and undergoing revascularization, the technique enables complete resection of the tumor, which in turn improves patient survival. However, the procedure is complex and risky, and patients may experience serious complications such as massive bleeding, narrowing of blood vessels, blockage of blood vessels, and thrombosis after the procedure. Arterial sheath exfoliation technology refers to the radical resection of the tumor by delicately stripping the tissue between the tumor and the arterial sheath, while avoiding direct damage to the artery, which has the advantages of low surgical risk, low complication rate, and ability to protect arterial function. However, its application scope is relatively limited, and it is mainly suitable for patients with locally advanced pancreatic cancer whose external elastic layer has not been invaded. Arterial resection and arterial sheath removal have made significant progress in the treatment of pancreatic cancer, but there are still many challenges. In the future, with the continuous progress of surgical technology and the deepening of the multidisciplinary comprehensive treatment model, as well as further in-depth research on the principles, advantages, limitations and clinical efficacy of these two technologies, it is expected that these two technologies will provide more effective methods for the treatment of locally advanced pancreatic cancer, and the clinical application effect will be further improved.