JCB, Volume 25, Number 4, 2020 Commentary Vol.25 No. 4 (2020) What’s Coming Next in Transformative Innovation? Arthur A Boni The idea in short. Contiguous with the publication of this special edition focused on the “Promises and Challenges of Transformative Innovation”, it is appropriate that we announc Commentary Vol.25 No. 4 (2020) Healthcare Pilgrim's Progress Peter Pitts Progress is both a noun (forward or onward movement toward a destination) and a verb (to move forward or onward in space or time). Innovation is a noun (the action o Article Vol.25 No. 4 (2020) Emerging, Transformative Technologies: Promises and Business Model Challenges Arthur Boni This issue provides a perspective on emerging, transformative technologies that promise to create innovations that are intended to provide solutions for significant problems in the biopha Article Vol.25 No. 4 (2020) An introductory perspective on emerging, transformative technologies in biopharma: promises, challenges and impediments Arthur A Boni This article provides a top-level overview of some key challenges and potential solutions associated with the development and commercialization of innovative and transformative solutions Article Vol.25 No. 4 (2020) A framework for comparing R&D productivity at big pharma companies vs. biotech startups Richard Murphey Biopharmaceutical research and development (R&D) productivity has been steadily declining for several decades. Preliminary evidence suggests that this trend is stabilizing or re Article Vol.25 No. 4 (2020) Personalized Medicine by Design Saul Kaplan Sometimes tweaks aren’t enough. Sometimes nothing short of reinventing yourself, your organization, or your community is called for. Today feels like one of those times. If anything is Article Vol.25 No. 4 (2020) Augmenting Healthcare with Human-Centered Technologies Christopher Moehle “Robotics”, “Artificial Intelligence”, and “Machine Learning” have become an almost impossibly broad amalgam of terminologies that span across industries to include everything Article Vol.25 No. 4 (2020) Solving Hard Problems with AI: Dramatically Accelerating Drug Discovery Through A Unique Public-Private Partnership John Baldoni Dramatic disruptions in technologies can result in the creation of new markets, the emergence of new paradigms, and the displacement of entrenched approaches and business models. This can Article Vol.25 No. 4 (2020) Lessons from Sovaldi: Fueling Innovation While Ensuring Access Marc Watrous The case of Gilead Science’s hepatitis C therapy Sovaldi is a notable precursor to the larger debate over drug pricing, providing some important lessons, at a time when a new gener From the Boardroom Vol.25 No. 4 (2020) The “Art of Collaborations”: Understanding the Anatomy of Transformative Transactions in Biopharma Arthur A Boni This article highlights the factors that drive successful collaborations and partnerships that underlie accessing transformative technologies, and financially sharing of value created thr From the Boardroom Vol.25 No. 4 (2020) Commercializing the new frontier in DNA writing: Enzymatic synthesis Michael J. Kamdar This article provides an overview of the emerging technology of enzymatic DNA synthesis, which holds the promise of making the business of writing DNA cost-effective, faster, sustainable, From the Boardroom Vol.25 No. 4 (2020) Challenges for Transformative Innovation in Emerging Digital Health Organizations: advocating service design to address the multifaceted healthcare ecosystem Arthur A Boni This article uses mini- case studies of three early stage organizations that pursued different pathways or models for bringing emerging, transformative digital technologies to the healthc From the Boardroom Vol.25 No. 4 (2020) Legal and Compliance Considerations When Bringing Cellular Therapies to Market Amy Dow Cellular therapies treat the underlying cause of disease by removing cells from a patient’s body, modifying the cells by introducing a new gene or correcting a faulty one, and then infu Original Article Vol.25 No. 4 (2020) Application of Image Feature Extraction in Traffic Road Centerline Recognition based on agricultural development Shuang Shi In order to improve the recognition efficiency of traffic road centerline recognition method, a traffic road centerline recognition method based on speech recognition technology and image Original Article Vol.25 No. 4 (2020) Deep learning based high similarity automatic retrieval algorithm for vocabulary interpretation of workers of Food Sector in china Xuezhong Wu In order to build a high similarity English vocabulary interpretation domain knowledge base and ensure the automatic retrieval effect of high similarity English vocabulary interpretation, Original Article Vol.25 No. 4 (2020) Design of English Writing Assessment System Based on AI Technology in food and agriculture sectors Lei Jin At present, the ability of distinguishing words in intelligent composition evaluation system is poor, which leads to poor evaluation effect. Aiming at this problem, this paper puts forwar Original Article Vol.25 No. 4 (2020) The vocabulary of agriculture semi-popularization articles in English: A corpus-based study Qiaoli Quan Based on the obtained research results, this paper makes an in-depth study of English vocabulary interpretation retrieval technology, and proposes a corpus based automatic retrieval techn
