The economic potential of plant-made pharmaceuticals in the manufacture of biologic pharmaceuticals

James Kaufman
Nicholas Kalaitzandonakes

DOI:https://doi.org/10.5912/jcb376

Abstract:

Biologic pharmaceuticals have emerged to treat a number of diseases such as cancer and immune disorders. Although these drugs provide significant benefits, they have tended to be costly to produce. Production technologies that grow biologic drugs in plants offer the potential to lower those costs. This article uses a system of simulation models to compare the economics of plant made pharmaceuticals (PMP) to incumbent productions systems. Although it is found that significant cost savings are possible, RD investment in PMPs continue to be limited, which suggests that there are a number of obstacles that limit adoption.

Keywords:plant-made pharmaceuticals ,monoclonal antibodies ,therapeutic biologics ,manufacturing ,en ,